Recent University-Based Science Research Study
New & Improved HairGenesis Generation 4
are the First Two Mechanism of Action Hairloss Products

Combats Two Causes of Hairloss:
- harmful DHT in the body & on the scalp
- Inflammation in the hair follicles.

NO OTHER HAIRLOSS TREATMENT,
whether Drug or Non-Drug, treats two (2) causes of Hairloss!


Click to Read the Study:
Evidence Based Complementary Alternative Medicine

Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract

Researchers: Sridar Chittur¹, Brian Parr¹ and Geno Marcovici²

¹ State University of New York (SUNY), Albany, NY
² Advanced Restoration Technologies (HairGenesis), Inc., Phoenix, AZ

Chronic inflammation of the hair follicle is considered a contributing factor in the patho-genesis of AndroGenetic Alopecia (AGA). Previously, we clinically tested LipoSterolic Extract of Serenoa repens (LSESr - Saw Palmetto) and its glycoside, Beta-Sitosterol, in subjects with AGA and showed a highly positive response to treatment. In the most recent University-based science study, we sought to determine whether blocking of inflammation using a composition containing LSESr as well as two Anti-Inflammatory agents (carnitine and thioctic acid) could alter the expression of molecular markers of inflammation in a well-established in vitro system.

Using a well-validated assay representative of hair follicle keratinocytes, specifically, stimulation of cultured human keratinocyte cells in vitro, we measured changes in gene expression of a spectrum of well-known inflammatory markers. Lipopolysaccharide (LPS) provided an inflammatory stimulus. In particular, we found that the composition effectively suppressed LPS-activated gene expression of chemokines, including CCL17, CXCL6 and LTB(4) associated with pathways involved in inflammation and apoptosis.

Our data supports the hypothesis that the test compound exhibits Anti-Inflammatory characteristics in a well-established in vitro assay representing hair follicle keratinocyte gene expression. These findings suggest that 5-Alpha Reductase inhibitors (5AR Inhibitors), also known as DHT Blockers, combined with blocking of inflammatory processes could represent a unique two-pronged approach (Dual Mechanism of Action) in the treatment of pattern hair loss with improved effectiveness over all other current hair loss treatment products.

No other non-Drug / botanical hairloss treatment remedy has even One (1) research study published in a Peer-Reviewed Medical Journal. But now, Hair Genesis, is Supported by TWO (2) published research studies, including our recent landmark University-based study which led to the development of our newest and most effective Generation 4 formulations ever. Just published in 2009, in the prestigious Peer-Reviewed Medical Journal:

Click to Read the Study: Evidence Based Complementary Alternative Medicine